Testing EXL01 to prevent Crohn's disease return after surgery
Part of Digestive system clinical trials.
This study tests a new oral treatment called EXL01 to see if it can prevent Crohn's disease from coming back after surgery to remove part of the small and large intestine. It may be an option if you are not planning to use strong immune-suppressing drugs (except anti-TNF) in the next 6 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have Crohn's disease that affects your ileum (last part of the small intestine) and possibly your colon.
- You had surgery to remove the ileocecal valve and the end of the small intestine (ileocecal resection) between 5 days and 5 weeks before joining.
- Your doctor plans for you to either take no Crohn's medicine or only anti-TNF drugs for the next 6 months after surgery.
- You do not have active anal fistulas, a stoma, or recent complications from surgery.
- You have not had more than 2 small bowel surgeries or had more than 50 cm of intestine removed total.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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