CBD plus opioid treatment for recovery
Treatments studied
Part of Mental health clinical trials.
This study tests whether adding cannabidiol (CBD) to your usual methadone or buprenorphine treatment helps you recover from opioid use disorder. If you're already in stable treatment with those medications, the trial aims to see if CBD can improve your outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 to 65 years old.
- You should have opioid use disorder and be on methadone (at least 10 mg daily) or buprenorphine (at least 2 mg daily) for at least 14 days.
- You need to be stable enough to avoid acute withdrawal or intoxication at the study visits.
- You cannot have certain medical conditions like severe liver or kidney problems, or a prolonged heart rhythm on EKG.
- You must agree to use effective contraception if you are of childbearing potential.
- You cannot be taking certain medications or supplements that could interact with CBD in the past 14 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether two cannabis-like medicines, dronabinol and Epidiolex, can help reduce withdrawal symptoms and other discomforts people may feel when they first start taking buprenorphine for opioid use disorder. If you've recently started buprenorphine and still have symptoms, this study might offer extra relief.
This study tests whether a combination of THC and CBD can help people who have both opioid use disorder and chronic low back pain. You would need to be on a stable dose of methadone and have used cannabis at least once in your life.
This trial tests whether psilocybin can help people recovering from opioid use disorder while living at a residential treatment center. If you are already taking buprenorphine/naloxone (Suboxone), methadone, or have received Sublocade, this study may be an option for you.
This study uses MRI scans over time to track brain changes in people with opioid use disorder who recently started methadone treatment. You can help researchers understand recovery patterns if you are early in your methadone journey and can commit to repeated visits.
This trial studies a program meant to improve treatment access and support recovery for people with opioid use disorder who also have mental health symptoms. It may help if you are new to the program or recently relapsed, or if mental health symptoms have worsened—even without a relapse.
This trial tests whether starting buprenorphine using a low-dose plan is a safe and workable way to treat opioid use disorder. You may be able to join if you are 18+, have opioid use disorder, and can follow the study medication and visits.
Hear when a new Opioid Use Disorder (OUD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.