Study of deucravacitinib for psoriasis with eczema features
Treatments studied
Part of Skin clinical trials.
This trial tests an oral medication called deucravacitinib for people who have both psoriasis and eczema (or psoriasis that looks like eczema) on their skin. The goal is to see if it can help reduce the severity of their plaques and itch.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with moderate to severe plaque psoriasis with eczematous features (patches that look like both psoriasis and eczema).
- Your skin involvement is at least 3% of your body surface area (BSA) and your doctor has rated your psoriasis as at least 3 on the IGA scale (0-5).
- You have not used strong topical medications (like steroid creams or calcineurin inhibitors) on the affected areas for at least 2 weeks before starting the study.
- You have not received biologic treatments (like injectable psoriasis medicines) or certain oral immunosuppressants (like cyclosporine, methotrexate, or JAK inhibitors) for at least 4 weeks (or 5 half-lives) before starting.
- You do not have active autoimmune diseases, active tuberculosis, hepatitis B, or uncontrolled serious health problems (like heart failure or liver/kidney disease).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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