Clinical trials
Psoriasis clinical trials
A skin condition that causes a rash with itchy, scaly patches. We’re tracking 165 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04950218Recruiting
Study risks of heart problems in people with psoriasis
This study asks adults with psoriasis about factors that may be linked to heart problems. It aims to better understand who is at higher risk, which could help guide future prevention and care.
Hellerup, CopenhagneAges 18 years+ - NCT07780929Recruiting
Study of XJH05 ointment for mild-to-moderate plaque psoriasis
This trial tests a new ointment (XJH05) for people with mild-to-moderate plaque psoriasis. It aims to see if this treatment helps reduce symptoms and is safe for topical use.
Xi'an, ShaanxiAges 18–65 - NCT07234591Recruiting
Study of an oral medication for moderate to severe plaque psoriasis
This study tests an experimental oral medication (a TYK2 inhibitor) for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at reducing psoriasis symptoms.
ShanghaiAges 18–70 - NCT07545902Recruiting
Urea-based creams for plaque and palm-sole psoriasis
This study tests two medicated creams containing urea (a natural moisturizing ingredient) to treat psoriasis on the skin and on the palms and soles of the feet. The creams may help reduce flaking, scaling, and irritation in people with mild psoriasis.
Chieti, ItaliaAges 18–65 - NCT03392337Recruiting
Narrowband UVB light therapy for moderate to severe plaque psoriasis
This study tests whether narrowband ultraviolet B (UVB) light given three times a week for 12 weeks improves moderate-to-severe plaque psoriasis. It is an “open-label” pilot, meaning everyone gets the UVB treatment and researchers track how your skin responds.
East Windsor, New JerseyAges 18 years+ - NCT03827876RecruitingPhase 4
Enstilar added to Enbrel or Humira for plaque psoriasis
This trial tests whether adding Enstilar (a skin spray/foam medication) on top of your usual injection—Enbrel or Humira—works better for plaque psoriasis. You might be a candidate if your psoriasis affects a moderate amount of skin and you’ve been on Enbrel or Humira long enough.
East Windsor, New JerseyAges 18 years+ - NCT04347473RecruitingPhase 4
ILUMYA plus halobetasol ointment for plaque psoriasis
This trial studies whether ILUMYA (an injection) working together with halobetasol ointment helps control moderate-to-severe plaque psoriasis. It is meant for adults whose psoriasis is significant enough that they may need light therapy (phototherapy) and/or pills/injections (systemic therapy).
East Windsor, New JerseyAges 18 years+ - NCT04372277RecruitingPhase 4
Adding Enstilar to Taltz for plaque psoriasis
This trial studies whether using Enstilar (a medicated skin spray/foam) together with Taltz works better than staying on Taltz alone for chronic plaque psoriasis. It focuses on adults with a specific amount of body skin affected by psoriasis who have already been on Taltz for at least 24 weeks.
East Windsor, New JerseyAges 18 years+ - NCT06987292Recruiting
Studying IL-17 inhibitors for hidden tendon inflammation in psoriasis
This study tests whether IL-17 inhibitor medications can reduce inflammation in tendons and ligaments that is not visible on the skin but can be detected with a special ultrasound. It may be an option for people with moderate to severe psoriasis who have not had enough relief from creams or light therapy.
Nanjing, JiangsuAges 18 years+ - NCT07149792RecruitingPhase 4
Personalized treatment study for psoriasis and joint health
This study tests whether a personalized treatment plan can help people with psoriasis and psoriatic arthritis, and also looks at how these conditions affect the heart. The goal is to find better ways to treat you and protect your heart health.
Taichung, TaiwanAges 18–75 - NCT07370766Recruiting
Tildrakizumab for moderate-to-severe psoriasis in Canada
This study looks at how well tildrakizumab works for people with moderate-to-severe plaque psoriasis who are starting this treatment through a support program in Canada. Researchers want to see how it affects your symptoms and daily life.
Burlington, OntarioAges 18 years+ - NCT07426120RecruitingPhase 3
Coumarin cream for psoriasis: a research study
This study tests a cream made from a natural plant compound (coumarin) to see if it can help treat plaque psoriasis. If you have mild-to-moderate psoriasis and haven't used certain other treatments recently, this trial may be an option for you.
New York, New YorkAges 18–70 - NCT07432815RecruitingPhase 4
Psoriasis with depression: methotrexate plus an antidepressant
This trial tests if adding an antidepressant (escitalopram) to standard methotrexate treatment works better than methotrexate alone for people who have both psoriasis and depression or anxiety. If you have moderate to severe psoriasis and also struggle with depression or anxiety, this study might offer a way to treat both conditions together.
Cairo, Cairo GovernorateAges 18–60 - NCT07746583Recruiting
Switching from ustekinumab to guselkumab for psoriasis
This study is testing a medicine called guselkumab (Tremfya) for people with psoriasis who are already taking another biologic medicine, ustekinumab, but need to switch. The goal is to see how well guselkumab works in real-world use.
BudapestAges 18 years+ - NCT02707341Recruiting
Psoriasis patient registry to help researchers study treatments
This registry collects information from adults with psoriasis to better understand how psoriasis affects people and how treatments are used in real life. It may help future research and improve knowledge about treatment patterns and outcomes.
Waltham, MassachusettsAges 18 years+ - NCT07648602Recruiting
Tracking how psoriasis responds to new advanced treatments
This study follows patients with moderate to severe psoriasis who are starting a new advanced medication for the first time. Researchers will track how well the treatment works early on to understand what helps different patients improve.
Waltham, MassachusettsAges 18 years+ - NCT07116967RecruitingPhase 3
Long-term safety of two psoriasis drugs in people with heart risk
This study compares two medications for psoriasis (deucravacitinib and ustekinumab) over a long period. It's designed for people with moderate-to-severe psoriasis who also have certain risk factors for heart disease, like high blood pressure or diabetes.
Birmingham, AlabamaAges 40 years+ - NCT07719530RecruitingPhase 2
Testing SHR-1139 injection for moderate to severe psoriasis
This study tests a new injection called SHR-1139 for people with moderate-to-severe plaque psoriasis. The goal is to see if it can safely improve your skin condition.
Guangzhou, GuangzhouAges 18 years+ - NCT04772079RecruitingPhase 3
Test drug safety and effectiveness for youth plaque psoriasis
This study checks whether deucravacitinib works well and is safe in children and teens with moderate to severe plaque psoriasis. It also looks at drug levels in the body to help understand how the treatment behaves over time.
Ciudad Autonoma de Buenos Aires, Buenos AiresAges 4–18 - NCT07683065Recruiting
Secukinumab treatment in psoriasis patients with liver condition
This study looks at how well secukinumab works for psoriasis patients who also have a type of fatty liver disease called MASLD. It may help doctors understand if this treatment is a good option for people with both conditions.
Badalona, BarcelonaAges 18–100 - NCT06979453RecruitingPhase 3
A study of deucravacitinib for teens with plaque psoriasis
This trial tests an investigational oral medication called deucravacitinib for teenagers (adolescents) with moderate to severe plaque psoriasis. It aims to see if the drug is safe and works well.
Birmingham, AlabamaAges 12–17 - NCT07474792RecruitingPhase 2
Study of ORKA-002 for moderate-to-severe plaque psoriasis
This trial tests an investigational drug called ORKA-002 for people with moderate-to-severe plaque psoriasis. It aims to see how well different doses work and if they are safe. You may qualify if your psoriasis covers at least 10% of your body or if it has not responded well enough to other treatments.
Birmingham, AlabamaAges 18–79 - NCT06842199RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This trial tests an experimental drug called ICP-488 for people with moderate to severe plaque psoriasis. It aims to see if the drug can improve symptoms and is safe, and may be an option if you need stronger treatment than creams or light therapy.
Hefei, AnhuiAges 18–75 - NCT04537689RecruitingPhase 4
Test ixekizumab and stopping it in plaque psoriasis
This study looks at how well ixekizumab (an injection medication) works for moderate-to-severe plaque psoriasis, and what happens when the treatment is withdrawn. It may help you learn whether stopping the medicine is safe and how skin disease outcomes change over time.
Outram ParkAges 22–90
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Psoriasis trials by city
Studies with a site in or near these metro areas.
Psoriasis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for psoriasis?
- Yes. Clin2 currently lists 165 recruiting psoriasis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psoriasis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psoriasis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.