Direct oral challenge for kids with beta-lactam allergy in private practice
Part of Immune system & allergy clinical trials.
This trial studies a direct oral challenge (giving a small dose of the medicine by mouth) to safely confirm whether children truly have a mild, delayed allergy to certain antibiotics like amoxicillin. It aims to help remove inaccurate allergy labels so kids can use these common antibiotics if needed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Child is between 0 and 17 years old.
- The child had a suspected delayed allergy to amoxicillin, amoxicillin-clavulanate, cefpodoxime, or cefixime.
- The reaction started more than 1 hour after taking the medicine and was mild (like hives or a rash).
- There were no serious warning signs like severe skin peeling, blisters, mouth or eye swelling, fever, or organ problems.
- The child had a direct oral challenge in a private doctor's office and a follow-up visit 7 to 14 days later.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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