Clin2
NCT07023484Possibly a fitRecruiting

Timing of ovarian cancer surgery after chemo

Ovarian CancerFallopian Tube CancerPrimary Peritoneal Carcinoma

Treatments studied

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This study looks at whether the timing of surgery after chemotherapy can be personalized for advanced ovarian cancer. It uses a blood test (CA125) to help decide the best time for surgery, aiming to improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
126 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have advanced ovarian, fallopian tube, or primary peritoneal cancer that cannot be removed with upfront surgery.
  • You are scheduled to receive chemotherapy with carboplatin and paclitaxel before surgery.
  • You have a baseline CA125 blood test result that is at least twice the upper limit of normal.
  • You are willing to have surgery after chemotherapy if the cancer becomes operable, and more chemo after surgery.
  • You have had a BRCA or HRD gene test (either from your blood or tumor tissue).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07022535Recruiting· Phase 2
Personalized timing of surgery for advanced ovarian cancer

This trial checks if adjusting the timing of surgery (interval debulking surgery) after chemotherapy can improve outcomes for people with advanced ovarian cancer. It's for those who cannot have surgery right away and will receive chemotherapy first.

Hong Kong
NCT05200260Recruiting· Phase 2
Surgery plus maintenance medicines for advanced ovarian cancer

This trial checks whether having surgery to remove as much tumor as possible, followed by ongoing targeted treatment, helps people with advanced ovarian (and related) cancers live longer and/or control cancer better. It specifically uses tumor-testing results to match patients and then continues treatment after surgery.

Foshan
NCT07382479Not yet recruiting
Neoadjuvant chemotherapy with KELIM-guided surgery timing for ovarian cancer

This study tests whether monitoring a tumor marker called KELIM can help doctors decide the best time for surgery in people with advanced ovarian, fallopian tube, or primary peritoneal cancer. Participants first receive chemotherapy to shrink tumors, then have surgery either at a planned time or later based on how the tumor marker changes.

NCT04515602Not yet recruiting· Phase 3
Comparing surgery first versus chemotherapy first for advanced ovarian cancer

This trial compares two ways of treating advanced ovarian cancer: having surgery first, or having chemotherapy first followed by surgery. The goal is to see which approach improves outcomes for patients.

Shanghai, Shanghai Municipality
NCT06902467Recruiting
Chemotherapy directly into the abdomen after surgery for advanced ovarian cancer

This trial tests giving chemotherapy directly into the abdomen (intraperitoneal) after optimal surgery for advanced ovarian cancer. It aims to see if this approach is safe and effective for women who have already received 3-4 cycles of chemotherapy before surgery.

Murcia
NCT05862740Recruiting
Surgery study for advanced ovarian cancer after chemotherapy

This study looks at how well a minimally invasive surgery (laparoscopic debulking) can remove tumor in people with advanced epithelial ovarian cancer. It may help doctors compare whether this approach is safe and effective for patients who need either upfront surgery or surgery after chemotherapy.

Padova, Padova, Veneto

Hear when a new Ovarian cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.