Topical TolaSure cream for epidermolysis bullosa simplex
Part of Genetic & congenital, Skin clinical trials.
This study tests a medicated cream called TolaSure on skin affected by epidermolysis bullosa simplex (EBS), a condition that causes fragile skin and blistering. The cream aims to reduce blistering and improve healing by targeting a faulty protein in the skin. It is for people with localized, intermediate, or severe EBS who are currently having active blistering.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Aged 2 years or older
- Diagnosis of localized, intermediate, or severe epidermolysis bullosa simplex (EBS) with a confirmed gene change in KRT5 or KRT14
- For localized EBS: blistering covering at least 15% of the bottom of one foot
- For intermediate or severe EBS: an active flare with blisters covering at least 2-3% of your body
- No infected skin areas or use of topical antibiotics on target skin within 14 days
- Able to avoid other topical creams or medicated dressings on the treated areas during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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