Organoids for brain tumors: testing treatment response in the lab
Part of Cancer clinical trials.
This study tests a new way to grow miniature versions of your brain tumor in the lab (called organoids) from a small piece of your tumor removed during surgery. The results may help doctors understand which treatments might work best for you in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Your doctor thinks you have a fast-growing type of brain tumor (high-grade glioma) based on an MRI scan
- You are scheduled for surgery to remove the tumor
- You are well enough to receive radiation therapy and a chemotherapy drug called temozolomide after surgery, possibly along with Tumor-Treating Fields (a device that sends low-frequency electric fields to the brain)
- You do not have any other cancer that has been active in the past 2 years
- You are not pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial uses a lab-grown model of your tumor (called an organoid) to test whether different drugs might work against it. The goal is to find the best treatment for your specific glioblastoma.
This trial uses a sample of your tumor removed during surgery to grow tiny 3D models (organoids) in a lab. These models help doctors test which drugs might work best for your specific glioblastoma.
This study tests a new way to choose treatment for people with brain tumors that have not responded to standard therapies. Your tumor sample is analyzed in the lab to find which drugs might work best for you, and then you receive a personalized treatment plan.
This early-phase trial tests a tiny implanted device placed during brain tumor surgery. It delivers very small doses of medicine directly to the tumor area for a short time, aiming to see if this approach is safe and workable in patients with certain gliomas.
This trial uses special lab models (“immune organoids”) to study certain cancers in children and young people. It may help researchers learn what those cancers do and improve future treatment ideas.
This trial uses a special lab technique (called organoids) to grow a mini version of your tumor from a biopsy sample. Researchers will test different treatments on these mini-tumors to see which one might work best for you.
Hear when a new Glioblastoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.