Clin2
NCT07029529Possibly a fitRecruiting

Apremilast for alcohol use disorder

Alcohol Use Disorder

Treatments studied

Part of Mental health clinical trials.

This study tests whether a drug called apremilast can help people who drink heavily reduce their alcohol use. You will take the medication daily for several weeks and attend study visits to track your progress.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
80 people
Ages
21 years to 65 years
Study type
Interventional

Who can take part

  • You are between 21 and 65 years old.
  • You have a diagnosis of alcohol use disorder in the past 6 months.
  • If you are a man, you drink more than 14 drinks per week and have more than 4 drinks in a day at least twice a week. If you are a woman, you drink more than 7 drinks per week and have more than 3 drinks in a day at least twice a week.
  • You are able to take oral medication and follow the study schedule.
  • You are not currently in treatment for drinking or trying to quit on your own.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06489782Recruiting
New approach to test alcohol use disorder medications

This study tests a new way to quickly screen medications for alcohol use disorder (AUD). You will have lab sessions where your drinking is monitored to see how different medicines affect your alcohol use.

New Haven, Connecticut
NCT06900998Not yet recruiting· Phase 2
Nimodipine for reducing alcohol drinking

This study tests whether the medication nimodipine (usually used for blood pressure) can help people who drink heavily reduce how much they drink. If you join, you may receive the medication or a placebo (a pill with no active ingredient) and take part in drinking sessions to see how it affects you.

New Haven, Connecticut
NCT06349083Recruiting· Phase 2
Psilocybin-assisted treatment for alcohol use disorder

This study tests whether psilocybin, a psychedelic drug, combined with therapy can help people reduce or stop drinking. It aims to understand how psilocybin affects the brain and behavior in people with alcohol use disorder.

New York, New York
NCT07681869Not yet recruiting· Phase 2
Nimodipine for reducing alcohol drinking

This study tests if a blood-pressure medicine called nimodipine can help people who drink heavily reduce their alcohol intake. The trial involves lab-based drinking sessions and brain scans to understand how the drug works on the brain.

New Haven, Connecticut
NCT07325266Recruiting· Phase 2
Testing apremilast for alcohol use disorder

This study tests whether a pill called apremilast can help reduce drinking in people with alcohol use disorder. You'll take the medication and attend regular visits to see how it affects your alcohol cravings and use.

Los Angeles, California
NCT04066192Recruiting· Phase 2
Brexpiprazole trial for alcohol use disorder in adults

This study tests whether brexpiprazole can help adults with alcohol use disorder. You must currently not be taking alcohol-focused treatment or alcohol medicines, and you’ll likely complete questionnaires and brain scans.

Aurora, Colorado

Hear when a new Alcohol Use Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.