Clin2
NCT07060794Possibly a fitNot yet recruiting

Tafenoquine plus standard malaria drugs for vivax malaria

Vivax Malaria

Part of Infections clinical trials.

This trial tests a combination of antimalarial drugs (tafenoquine plus artemisinin-based combination therapies) to see if it's safe and effective for treating vivax malaria. Participating may help clear the infection and prevent it from coming back.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
507 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have Plasmodium vivax malaria (a common type of malaria).
  • Your G6PD enzyme levels must be normal (tested before starting).
  • You should have a fever now or have had one in the last 48 hours.
  • You must be 18 years or older.
  • Your hemoglobin (a blood protein) must be at least 8 g/dl.
  • You can't be pregnant, breastfeeding, or have a history of psychiatric disorders.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06148792Recruiting· Phase 3
Testing a new dose of tafenoquine for vivax malaria

This trial tests a revised dose of a medicine called tafenoquine to more effectively cure vivax malaria (a type of malaria that can come back). It is for people with normal G6PD enzyme levels and a current fever from vivax malaria.

Manaus
NCT07468513Recruiting· Phase 4
Primaquine for vivax malaria in G6PD-intermediate or deficient adults

This trial tests how well the drug primaquine works for people with vivax malaria who have intermediate or low levels of an enzyme called G6PD. It aims to find safe and effective treatment options for this group.

Manaus
NCT07835321Not yet recruiting· Phase 2
Tafenoquine drug levels in small children

This study tests how the malaria medicine tafenoquine is processed in the bodies of young children with vivax malaria. It helps find the right dose for small children and ensures the treatment is safe and effective.

Mae Ramat, Changwat Tak
NCT05788094Recruiting· Phase 4
Compare two medicines for P. vivax malaria

This study tests how well a malaria treatment plan works for people with P. vivax malaria who don’t have another malaria type at the same time. It aims to see whether adding or using different medicines (ACT vs chloroquine with tafenoquine) helps clear infection and prevent return of disease.

Mae Sot, Changwat Tak
NCT07533136Not yet recruiting
Combination treatment for vivax malaria relapse prevention

This trial tests whether combining tafenoquine with other malaria medicines works better than a single drug for curing vivax malaria and preventing it from coming back. You would receive the study drugs and be monitored for about 6 months.

Ratchathewi, Bangkok
NCT04704999Recruiting· Phase 4
Testing the right tafenoquine dose for malaria prevention

This study tests the best dose of tafenoquine to treat people with symptoms from a malaria type called P. vivax and to help prevent it from coming back. You may be eligible if you recently had fever and meet specific blood and safety checks, especially G6PD level.

Siem Reap

Hear when a new Vivax Malaria trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.