Clin2
NCT07468513Possibly a fitRecruiting

Primaquine for vivax malaria in G6PD-intermediate or deficient adults

Vivax MalariaG6PD Deficiency

Part of Blood & lymphatic, Genetic & congenital, Hormones & metabolism, Infections clinical trials.

This trial tests how well the drug primaquine works for people with vivax malaria who have intermediate or low levels of an enzyme called G6PD. It aims to find safe and effective treatment options for this group.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a confirmed vivax malaria infection (and no other type of malaria).
  • Your G6PD level is intermediate (30% to less than 70% of normal) or deficient (30% or less of normal).
  • You currently have a fever (temperature 37.5°C or higher) or have had a fever in the last 48 hours.
  • You are 18 years old or older.
  • Your hemoglobin level (a measure of red blood cells) is at least 8 g/dL.
  • You live in the study area and are willing to be monitored for 6 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06148792Recruiting· Phase 3
Testing a new dose of tafenoquine for vivax malaria

This trial tests a revised dose of a medicine called tafenoquine to more effectively cure vivax malaria (a type of malaria that can come back). It is for people with normal G6PD enzyme levels and a current fever from vivax malaria.

Manaus
NCT07060794Not yet recruiting· Phase 4
Tafenoquine plus standard malaria drugs for vivax malaria

This trial tests a combination of antimalarial drugs (tafenoquine plus artemisinin-based combination therapies) to see if it's safe and effective for treating vivax malaria. Participating may help clear the infection and prevent it from coming back.

NCT07835321Not yet recruiting· Phase 2
Tafenoquine drug levels in small children

This study tests how the malaria medicine tafenoquine is processed in the bodies of young children with vivax malaria. It helps find the right dose for small children and ensures the treatment is safe and effective.

Mae Ramat, Changwat Tak
NCT07468526Not yet recruiting· Phase 3
Short-course primaquine for vivax malaria treatment

This trial tests a shorter course of the drug primaquine to prevent relapse of vivax malaria, a recurring type of malaria. It may offer a faster recovery with fewer doses.

Arba Minch, Arba Minch
NCT07060404Not yet recruiting· Phase 2/Phase 3
Breast milk study for mothers with past vivax malaria

This study tests a medicine given to mothers after childbirth to see how it passes into breast milk and if it is safe for babies. It may help prevent malaria relapse in mothers who have had vivax malaria.

Madang, Madang Province
NCT06666491Recruiting· Phase 3
Comparing two malaria treatments for P. vivax in people 2 and older

This study compares two medicines (tafenoquine and primaquine) taken with chloroquine to treat P. vivax malaria. It aims to see which is safer and works better in Indian participants aged 2 to 64.

Ahmedabad

Hear when a new Vivax Malaria trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.