Serum vs hydroquinone for melasma treatment
Part of Skin clinical trials.
This trial compares a new cosmetic serum to a standard treatment (4% hydroquinone) for facial melasma over 84 days. It may help if you have mild to moderate melasma and are looking for a gentler alternative.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old
- You have mild to moderate facial melasma (a skin condition causing dark patches), confirmed by a doctor
- Your skin type is light to medium brown (Fitzpatrick type II to V)
- You are willing to avoid too much sun and use the provided sunscreen
- You are generally healthy and not pregnant or breastfeeding
- You have not used other melasma treatments or certain medications in the past 4 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a microneedling technique combined with three topical medications (metformin, tranexamic acid, and a modified Kligman's formula) to treat melasma, a common skin condition causing dark patches. The goal is to see if this approach safely and effectively reduces melasma in eligible women.
This trial compares a cream containing metformin with a 3-part cream combination to see which is better at fading melasma, a common skin darkening condition. You would apply one of the creams daily and be monitored for improvement.
This study tests whether adding an oral medication (tranexamic acid) to a standard triple cream for melasma works better than the cream alone. It may help if you have medium-to-severe melasma and are generally healthy.
This trial tests a new way to deliver a medicine (tranexamic acid) into melasma patches using ultrasound waves. It aims to see if the ultrasound helps the medicine work better to lighten the dark spots.
This trial tests if adding a special serum to laser treatment can better treat dark spots from acne and melasma in women with medium to dark skin tones. The serum contains ingredients that may help lighten spots and improve skin tone.
This trial tests a daily routine of facial products to see if they can reduce dark patches (melasma) on your face. It is for people who have had melasma for at least a year and have not used certain creams like retinoids or hydroquinone recently.
Hear when a new Melasma (Facial Melasma) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.