Serum vs hydroquinone for melasma treatment
Part of Skin clinical trials.
This trial compares a new cosmetic serum to a standard treatment (4% hydroquinone) for facial melasma over 84 days. It may help if you have mild to moderate melasma and are looking for a gentler alternative.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old
- You have mild to moderate facial melasma (a skin condition causing dark patches), confirmed by a doctor
- Your skin type is light to medium brown (Fitzpatrick type II to V)
- You are willing to avoid too much sun and use the provided sunscreen
- You are generally healthy and not pregnant or breastfeeding
- You have not used other melasma treatments or certain medications in the past 4 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a microneedling technique combined with three topical medications (metformin, tranexamic acid, and a modified Kligman's formula) to treat melasma, a common skin condition causing dark patches. The goal is to see if this approach safely and effectively reduces melasma in eligible women.
This trial tests a new way to deliver a medicine (tranexamic acid) into melasma patches using ultrasound waves. It aims to see if the ultrasound helps the medicine work better to lighten the dark spots.
This study tests a cosmetic cream to reduce dark spots on the face, including melasma and sun spots. It aims to see if the product improves the appearance of hyperpigmentation.
This study tests whether adding an oral medicine (tranexamic acid) to a standard triple cream works better for melasma than the cream alone. It may help lighten dark patches on your skin if you have the right type of melasma.
This study compares a metformin cream to a standard treatment (Kligman's regimen) for reducing melasma, a common skin condition causing dark patches on the face. It aims to find which treatment is more effective for women with this condition.
This study compares a cream containing metformin to a triple combination cream for treating melasma, which causes brown patches on the face. The goal is to see which treatment is more effective in lightening these patches.
Hear when a new Melasma (Facial Melasma) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.