Needle-assisted treatment for melasma using common skin medications
Part of Skin clinical trials.
This trial tests a microneedling technique combined with three topical medications (metformin, tranexamic acid, and a modified Kligman's formula) to treat melasma, a common skin condition causing dark patches. The goal is to see if this approach safely and effectively reduces melasma in eligible women.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 or older.
- You have been diagnosed with melasma (dark patches on your skin).
- You have not used any prescription treatments for melasma in the past 6 months.
- You are not pregnant or breastfeeding and do not use hormonal birth control.
- You do not have any serious health conditions that affect skin color (like liver, kidney, or thyroid problems).
- You do not have very dark skin (Fitzpatrick skin type V or VI) or a history of keloids (thick scars).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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