Pain and inflammation after one‑visit vs two‑visit root canal
Part of Mouth & dental, Pain clinical trials.
This trial compares pain levels and a protein linked to inflammation (MMP‑9) when a root canal on an infected, dead tooth is done in one visit versus two visits. The goal is to see which approach may be more comfortable for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 40 years old.
- You have a permanent tooth with a single straight root that is dead (non‑vital) and has a small infection at the tip (no bigger than about 2 mm).
- You have no swelling or pus coming from the tooth, and the tooth is not loose beyond a mild degree.
- You have not taken any anti‑inflammatory drugs or antibiotics in the last month.
- You are generally healthy (no major medical conditions) and not pregnant.
- This is the first time the tooth is being treated for a root canal.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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