Clin2
NCT07104591Possibly a fitAvailable

Expanded access to experimental virus treatment for children

Epstein-Barr Virus InfectionCytomegalovirus InfectionsAdenovirus InfectionBK Virus InfectionJC Virus InfectionViral Infections Post-TransplantPost-Allogeneic Stem Cell Transplant Complications

Part of Infections clinical trials.

This program offers an experimental treatment for children under 18 who have had a stem cell transplant or CAR T-cell therapy and are struggling with persistent viral infections like EBV or CMV. It may help when standard treatments haven't worked.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Ages
Up to 17 years
Study type
Expanded Access

Who can take part

  • Must be under 18 years old
  • Must have had a stem cell transplant or CAR T-cell therapy in Texas
  • Must have a persistent, worsening, or recurrent infection with EBV, CMV, adenovirus, or BK virus
  • Must have already tried standard treatment and the infection did not improve
  • Must have a treating doctor based in Texas

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07873970Not yet recruiting· Early Phase 1
Viral infection treatment with immune cells for children and young adults

This trial tests whether giving special immune cells (called cytotoxic T lymphocytes) can fight viruses like CMV, adenovirus, EBV, or BK virus that are not responding to usual treatments. It is for people aged 0 to 29 with weakened immune systems due to inherited conditions or previous transplants.

NCT06926894Recruiting· Phase 1
A cell therapy for viral infections in children and young adults

This trial tests a special immune cell treatment (R-MVST cells) for children and young adults who have had a stem cell or organ transplant and are fighting stubborn viral infections like EBV, CMV, ADV, or BK virus. The goal is to see if these cells can help control the viruses when standard medicines haven't worked well enough.

New York, New York
NCT06027879Enrolling by invitation· Phase 1/Phase 2
Anti-viral T-cell therapy for stubborn viral infections after transplant

This trial tests a treatment using specially grown T-cells (a type of immune cell) to fight certain viruses that won't go away with standard medicines. It is for people who have had a stem cell or organ transplant, or who have a weak immune system, and who are struggling with adenovirus, CMV, or EBV infections.

Pittsburgh, Pennsylvania
NCT05183490Recruiting· Phase 1
Cell therapy for repeated viral infections after transplant

This early-phase (Phase 1) study tests an immune cell treatment (R-MVST) to help people whose immune system has been weakened by a past transplant and who keep getting viral infections reactivated or not responding well to standard treatment. It may help your body control viruses like EBV, CMV, adenovirus, or BK virus.

New York, New York
NCT06909110Recruiting· Phase 1/Phase 2
Immune cells for viral infections after transplant

This trial tests a treatment using specially trained immune cells (virus-specific T-cells) to fight stubborn infections with adenovirus, CMV, or EBV in people with weakened immune systems, such as after a stem cell or organ transplant.

Palo Alto, California
NCT07368634Recruiting· Phase 1/Phase 2
EBV-TCR-T cells for persistent EBV after stem cell transplant

This trial tests whether special immune cells (called EBV-TCR-T cells) can help clear the Epstein-Barr virus in people who still have high virus levels after a stem cell transplant. It's an experimental therapy for those whose virus hasn't responded to standard care.

Beijing

Hear when a new Cytomegalovirus Infections trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.