Non-ischemic Cardiomyopathy Registry and Biobank
Part of Heart & circulation clinical trials.
This registry study collects information, blood samples, and MRI images from people with non-ischemic cardiomyopathy (a heart muscle disease not caused by blocked arteries). By joining, you help researchers better understand the condition and find new ways to diagnose and treat it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your heart's pumping ability (LVEF) is less than 50%, OR it is between 50% and 55% with signs of scarring or enlargement on an MRI AND you have a genetic mutation linked to non-ischemic cardiomyopathy.
- You do not have significant blockages in your heart arteries (70% or more in any artery, or 50% in the left main artery) or a history of a type 1 heart attack.
- You do not have other major heart conditions, like congenital heart disease needing surgery, moderate to severe valve disease, or specific types of cardiomyopathy such as amyloidosis, sarcoidosis, or those caused by chemotherapy.
- If you are over 70 and first saw a cardiologist for your heart muscle problem, you may still qualify, but only a small number of participants over 70 can be enrolled.
- You must be willing to have an MRI (called CMR) within 3 years of joining the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is a registry, meaning it collects health information to help doctors study heart muscle diseases and plan future cardiovascular studies. You may be able to join if you have a non-ischemic cardiomyopathy such as dilated cardiomyopathy, certain forms of thick heart muscle, non-compaction, or arrhythmogenic right-sided disease.
This study looks at different types of heart muscle diseases that are not caused by blocked arteries (non-ischemic cardiomyopathies). It aims to better understand how to diagnose, predict outcomes, and treat these conditions by gathering information from many patients over time.
This study uses heart MRI to find people with early signs of heart muscle disease who still have normal-sized heart chambers. It aims to better predict who is at risk so they can get earlier care.
This study builds a patient registry to collect information over time about several types of cardiomyopathy (heart muscle diseases). It may help researchers understand how these conditions progress and what care works best.
This study collects health records, heart ultrasound (echo), MRI images, and optional DNA testing for people with hypertrophic cardiomyopathy (HCM). It aims to build a large database to better understand HCM and support future research and care.
This study collects information from heart MRIs of people with hypertrophic cardiomyopathy, a condition where the heart muscle is unusually thick. The registry looks at how a special dye (gadolinium) highlights scarring in the heart, which may help doctors better understand and treat this condition.
Hear when a new Non-ischemic Cardiomyopathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.