Comparing two drugs to reduce pain from propofol injection
Treatments studied
Part of Pain clinical trials.
This trial tests two medicines, parecoxib and lidocaine, to see which works better at preventing the pain when propofol is given into a vein. It may help you if you are having elective surgery and want a more comfortable start to anesthesia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are in good health or have mild health problems (ASA grade I or II).
- You are having planned surgery that needs anesthesia.
- You can speak Arabic or English.
- You do not have liver cirrhosis or kidney failure.
- You are not allergic to lidocaine, parecoxib, or propofol.
- You are not pregnant.
- You do not have chronic pain or have taken pain medicine in the last hour.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether nalbuphine or lidocaine works better at reducing the pain felt when propofol is injected during general anesthesia. If you are having planned surgery with propofol, you may be able to join.
This trial tests three different medicines (lidocaine, paracetamol, and dexmedetomidine) to see which one works best to reduce the burning pain some people feel when the muscle relaxant rocuronium is injected during anesthesia. It's designed for adults having elective surgery under propofol.
This study compares two medications—ondansetron (a nausea-prevention drug) and lidocaine (a numbing agent)—to see which one better reduces the burning pain some patients feel when propofol is injected to start general anesthesia. If you're having elective surgery, this trial may help make your anesthesia experience more comfortable.
This study tests a new way to give propofol, the medicine that puts you to sleep for surgery, to reduce the burning or stinging pain it can cause when first injected. You may be able to join if you are having planned (non-emergency) surgery and are not given certain other medicines beforehand.
This study tests whether raising the arm during propofol injection reduces pain. Participants will be randomly assigned to have their arm elevated or not when the medication is given.
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