Comparing two medicines for injection pain during anesthesia
Treatments studied
Part of Pain clinical trials.
This study tests two different medicines to see which one works better at reducing the pain when propofol (a common anesthesia drug) is injected at the start of surgery. If you are having planned surgery, you may be able to take part and help find a way to make this injection more comfortable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You are generally healthy or have only mild medical conditions (ASA class 1 or 2)
- You are scheduled for an elective (non-emergency) surgery
- You speak Arabic or English
- You do not have liver cirrhosis, kidney failure, or allergies to lidocaine, parecoxib, or propofol
- You are not pregnant and do not have a chronic pain condition
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study compares two medicines—ondansetron (usually used for nausea) and lidocaine (a numbing medicine)—to see which one better reduces the pain you might feel when the anesthesia drug propofol is injected into your vein. If you are having planned surgery with general anesthesia, you may be able to help find a more comfortable way to start anesthesia.
This trial compares two medicines (nalbuphine and lidocaine) that are given through an IV before the anesthesia drug propofol, to see which one better prevents the burning or stinging pain some people feel when propofol is injected. If you are having planned surgery, this could make your anesthesia experience more comfortable.
This study compares three common pain relievers—lidocaine, paracetamol (acetaminophen), and dexmedetomidine—to see which works best to reduce the burning pain you might feel when the drug rocuronium is injected. If you are having planned surgery, this could help make your anesthesia experience more comfortable.
This study tests a new way of giving propofol, a medicine used to put you to sleep for surgery, in two steps to reduce the pain you might feel when it is injected. If you are having non-cardiac surgery with general anesthesia, this might make your experience more comfortable.
This study tests whether raising your arm before receiving propofol (a common sedative) through an IV can reduce or prevent the burning pain it often causes. If it works, it could make anesthesia more comfortable for many people.
This early study compares two anesthesia approaches during lumbar decompression (back surgery to relieve pressure on nerves). It may help improve comfort and safety during surgery, but whether you personally benefit is not yet known.
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