Ondansetron vs. Lidocaine to Reduce Propofol Injection Pain
Treatments studied
This study compares two medications—ondansetron (a nausea-prevention drug) and lidocaine (a numbing agent)—to see which one better reduces the burning pain some patients feel when propofol is injected to start general anesthesia. If you're having elective surgery, this trial may help make your anesthesia experience more comfortable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are in generally good health (ASA status I–III, meaning no serious medical conditions that would make surgery very risky)
- You are scheduled for elective (planned, non-emergency) surgery that will use general anesthesia with propofol
- You have not taken pain relievers or anti-nausea medications in the 12 hours before surgery
- You do not have a known allergy to ondansetron, lidocaine, or propofol
- You have an IV catheter placed in a vein on the back of your hand (a 20-gauge needle)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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