Comparing two medicines to reduce pain from anesthesia injection
Treatments studied
This study compares two medicines—ondansetron (usually used for nausea) and lidocaine (a numbing medicine)—to see which one better reduces the pain you might feel when the anesthesia drug propofol is injected into your vein. If you are having planned surgery with general anesthesia, you may be able to help find a more comfortable way to start anesthesia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years of age or older.
- You are scheduled for an elective (planned) surgery that uses general anesthesia with a drug called propofol.
- You have not taken pain relievers or anti-nausea medications in the 12 hours before surgery.
- You can communicate and describe your pain level clearly.
- You are not allergic to ondansetron, lidocaine, or propofol.
- You are not pregnant or breastfeeding, and you do not have chronic pain or use opioids regularly.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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