Testing a new toothpaste for early white spots on teeth
Part of Mouth & dental clinical trials.
This trial is testing whether a toothpaste made with bioactive silica and calcium can help reverse early white spot lesions (non-cavitated cavities) on teeth. If you have white spots on the front or back surfaces of your teeth that are not yet cavities, this study may be for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Have at least one white spot on a tooth that is not yet a cavity (non-cavitated lesion).
- The white spot must be on the front (facial) or back (lingual) surface of a tooth, near the gumline.
- The white spot should be an early sign of decay (score 1 or 2 on the ICDAS scale, or a Diagnodent reading between 14 and 20).
- You must not have any allergies to ingredients in the test toothpaste.
- You must not have any serious health condition or physical disability that could affect participation.
- You must not have white spots caused by other reasons, such as enamel problems from birth.
- If you are pregnant, you must not have frequent vomiting.
- You must not be a smoker.
- You must not have high exposure to acids from diet or environment.
- The white spot must not have a cavity or previous dental filling.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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