Toothpaste with calcium for early white spot lesions
Part of Mouth & dental clinical trials.
This study tests a special toothpaste (with bioactive silica and calcium) to see if it can help reverse early white spot lesions on teeth before they become cavities. It might help prevent the need for fillings by strengthening the enamel.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have at least one white spot (a chalky, whitish area) on a tooth that is not yet a cavity.
- The white spot should be on the front or back surface of a tooth, in the area near the gum line.
- The white spot must be in an early stage of decay, as confirmed by a dentist using special tools (ICDAS score 1 or 2 and Diagnodent reading between 14 and 20).
- You cannot have any allergies to the toothpaste ingredients or dental materials used in this study.
- You cannot have a medical condition or physical disability that would make participation difficult.
- You cannot be pregnant with frequent vomiting, a smoker, or have white spots due to other causes like enamel problems or acid exposure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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