Combination antifungal therapy for fungal infections in blood cancer
Part of Infections clinical trials.
This trial tests a combination of antifungal medicines (liposomal amphotericin B and either isavuconazole or posaconazole) for people with blood cancers who develop a fungal infection despite taking preventive antifungal drugs. It aims to find a better treatment for these difficult infections.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a blood cancer such as acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), or myelodysplastic syndromes (MDS).
- You developed a fungal infection while taking antifungal medication (like posaconazole or isavuconazole) for at least 7 days.
- You are not allergic or intolerant to any of the study drugs (liposomal amphotericin B, isavuconazole, or posaconazole).
- Your kidney and liver function tests are within acceptable limits (not severely elevated).
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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