A study of compression gloves and boots to prevent chemo nerve damage
Part of Brain & nervous system, Cancer, Pain clinical trials.
This trial is testing a wearable device (gloves and boots) that applies gentle compression to your hands and feet during chemotherapy. It aims to prevent or reduce nerve damage (numbness, tingling, pain) that some chemotherapy drugs can cause.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and have been diagnosed with a solid tumor cancer.
- You are scheduled to receive at least 4 cycles of chemotherapy that includes oxaliplatin (like FOLFOX or FOLFIRINOX), paclitaxel, or paclitaxel combined with carboplatin.
- You have no current numbness, tingling, or pain in your hands or feet from any cause.
- You have not received any nerve-damaging chemotherapy (like taxanes, platinum drugs, vinca alkaloids, or bortezomib) in the past year.
- You are willing to wear special gloves and boots (the Lilac device) during your infusion and for up to one hour after.
- You have no open wounds, sores, or allergies to latex on your hands, arms, feet, or legs where the device will be placed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether wearing a tight surgical glove during chemotherapy can help prevent nerve damage (peripheral neuropathy) in the hands. It is for people with breast cancer who are about to start a specific weekly chemo regimen.
This trial tests whether acupuncture and compression therapy can prevent nerve damage caused by taxane chemotherapy in early-stage breast cancer. It aims to reduce numbness, tingling, or pain in the hands and feet.
This study tests whether wearing cold gloves and socks during paclitaxel chemotherapy can prevent or reduce nerve damage in the hands and feet, a common side effect. If you are getting weekly paclitaxel for breast cancer, this might help keep your hands and feet more comfortable.
This trial tests if wearing special cooling gloves and socks during chemotherapy can help prevent nerve damage, tingling, or numbness in your hands and feet. It is for people with breast or gynecologic cancer who are starting certain types of chemo that can cause these side effects.
This trial tests if wearing compression gloves and socks during chemotherapy can prevent nerve damage in hands and feet caused by taxane or oxaliplatin treatment. It may help patients avoid numbness, tingling, or pain.
This trial tests if wearing compressive therapy (like special sleeves or stockings) during weekly paclitaxel chemotherapy can prevent nerve damage (peripheral neuropathy) in breast cancer patients. It is for people who have not yet had nerve issues or diabetes.
Hear when a new Chemotherapy Induced Peripheral Neuropathy (CIPN) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.