Sperm DNA test to predict varicocele surgery success
This study looks at whether a test that measures DNA damage in sperm (called sperm DNA fragmentation) can predict the success of a surgery to fix a varicocele. The surgery, called varicocelectomy, removes the swollen vein to improve sperm quality, and the study aims to help doctors know who might benefit most.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 20 and 45 years old.
- You must have a varicocele (a swollen vein in the scrotum) that is grade II or III, confirmed by a doctor's exam or ultrasound.
- You must have been trying to have a baby for at least a year without success (documented infertility).
- Your partner's fertility should be normal or have a treatable cause.
- You must not have certain health issues like previous scrotal injuries, infections, hormone treatment, or undescended testicles.
- You cannot smoke or work around x-rays or nuclear materials.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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