Study of CM512 injection for chronic hives
Treatments studied
Part of Immune system & allergy, Skin clinical trials.
This trial tests a new injection (CM512) for people with chronic spontaneous urticaria, also known as chronic hives. If you have had itchy hives for at least 6 weeks despite taking regular antihistamines, this study may help find a new treatment option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You must have been diagnosed with chronic hives for at least 6 months.
- You must have had itching and hives for more than 6 weeks while taking antihistamines.
- You must be on a stable dose of a second-generation antihistamine for at least 7 days before starting.
- Your hives and itching scores must be moderate to severe (UAS7 at least 16 and ISS7 at least 8) in the week before randomization.
- You cannot be pregnant, breastfeeding, or planning to have children during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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Other trials that look related to this one.
This trial tests a new oral medication for chronic spontaneous urticaria (chronic hives). It is a placebo-controlled study, meaning some participants will get the new drug and some will get a placebo (a pill with no active ingredient). The goal is to see if the new drug is safe and how well it works, possibly providing a new treatment option for those whose hives are not controlled by current antihistamines.
This trial tests an experimental drug called ICP-332 for people with chronic spontaneous urticaria (long-term hives) that is not well controlled by standard antihistamines. The goal is to see if the drug is safe and effective at reducing hives.
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