Extended antibiotics with methenamine for chronic urinary tract infection
Part of Infections, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial compares a longer, higher-dose antibiotic course combined with methenamine hippurate (a urinary antiseptic) against standard care (low-dose antibiotics or methenamine alone) for women with chronic urinary tract infections. It aims to see if the extended treatment is more effective at relieving persistent symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had daily urinary symptoms (like frequent urination, urgency, or bladder pain) for at least 3 months.
- A urine test shows a high number of white blood cells (a sign of infection).
- You are female (assigned female at birth) and at least 18 years old.
- Your kidney function is adequate (eGFR of 45 or higher).
- You can take at least one of the study antibiotics (cephalexin, nitrofurantoin, or trimethoprim) and methenamine hippurate.
- You are not pregnant, breastfeeding, or planning pregnancy during the trial, and you agree to use contraception if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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