Clin2
NCT07208006Possibly a fitRecruiting

Early cholesterol-lowering drug after heart attack

Acute Myocardial Infarction (AMI)

Treatments studied

Part of Heart & circulation clinical trials.

This trial tests whether giving a powerful cholesterol-lowering drug (PCSK9 inhibitor) very early after a heart attack can help prevent further heart problems. It is for people who have had a recent heart attack and have blockages in more than one heart artery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,518 people
Ages
18 years to 100 years
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You had a heart attack within the last 30 days, and it was your first hospitalization for it.
  • You have blockages in at least two heart arteries, and the main blockage was treated with a stent or balloon.
  • You have at least one other artery with a narrowing of 50% or more that is at least 2.5 mm wide.
  • You are willing to take study medications and come for follow-up visits.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06683131Not yet recruiting· Phase 4
Cholesterol-lowering injection before heart procedure for heart attack patients

This study tests whether giving a cholesterol-lowering injection (called a PCSK9 inhibitor) before a heart procedure to open blocked arteries can help people who are having a heart attack. The medicine may improve outcomes by lowering cholesterol quickly after the event.

Fuyang, Anhui
NCT04731155Recruiting· Phase 4
Test early PCSK9 medicine to prevent heart problems after a heart attack

This trial studies whether starting a cholesterol-lowering medicine called a PCSK9 inhibitor early after a heart attack can improve heart health and outcomes. It focuses on people who had a recent heart-artery procedure to fix the blockage in the left anterior descending (LAD) artery.

Shanghai, Shanghai Municipality
NCT05292404Recruiting· Phase 4
PCSK9 medicine soon after heart attack to protect the heart

This trial studies whether starting a PCSK9-blocking medicine early after a specific type of heart attack can improve heart outcomes. You may be eligible if you have a STEMI heart attack soon, are planning a procedure to open the blocked artery, and meet safety and pregnancy criteria.

Shanghai, Shanghai Municipality
NCT06854523Not yet recruiting
Early cholesterol-lowering treatment after a heart attack

This study tests whether starting a cholesterol-lowering injection (a PCSK9 inhibitor) early after a heart attack can slow or shrink the buildup of plaque in other heart arteries that are not the one that was stented. If you have two other arteries with mild blockages, this treatment might help prevent future heart problems.

Beijing, Beijing Municipality
NCT07824323Recruiting· Phase 4
Early cholesterol treatment after a heart attack

This study tests whether adding an extra cholesterol-lowering drug (bempedoic acid) to the usual treatment soon after a heart attack or related event can lower 'bad' cholesterol more effectively. It may help reduce the risk of future heart problems.

Taipei, Taipei City
NCT07290699Not yet recruiting· Phase 4
Rapid cholesterol-lowering within 24 hours after a heart attack

This trial tests whether giving a strong cholesterol-lowering treatment within 24 hours of a heart attack (during the procedure to open blocked arteries, called PCI) can reduce the risk of further heart problems. It aims to see if a rapid drop in cholesterol helps patients recover better.

Hear when a new Acute Myocardial Infarction (AMI) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.