Low dose naltrexone for fatigue in prostate cancer on hormone therapy
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This trial tests if a low dose of the drug naltrexone can help reduce fatigue in men with prostate cancer who are currently receiving hormone therapy (ADT). It may offer a new way to manage tiredness during treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have prostate cancer that has come back after initial treatment and have been on hormone therapy (ADT) for at least 3 months.
- If your cancer has spread, you may be on other hormone treatments like abiraterone or enzalutamide.
- You need to be in generally good health, able to perform daily activities (ECOG score less than 3).
- Your kidney, liver, and blood cell counts must be within acceptable ranges as determined by your doctor.
- You must score less than 43 on a fatigue questionnaire (FACIT-F) at screening, meaning you have at least moderate tiredness.
- You cannot have had chemotherapy in the last 3 months or be taking PARP inhibitors or any other experimental drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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