Low-dose naltrexone for nerve pain in people with HIV
Treatments studied
Part of Immune system & allergy, Infections, Pain clinical trials.
This trial studies whether a low dose of naltrexone can reduce long-lasting nerve-related pain in adults living with HIV. It may help if your pain has been ongoing and you have stable HIV control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 18 and 75 years old.
- You have HIV that has been well controlled: viral load under 1,000 copies/mL for the last 12 months.
- You have chronic nerve-related pain (pain linked to nerve problems) for at least 3 months, with average pain above 4 out of 10.
- You can speak English, understand the study, and agree to follow all study visits and rules.
- You cannot be pregnant or breastfeeding, and if you could get pregnant, you must use highly effective birth control during the study.
- You must not currently take opioid pain medicines and you can’t have needed opioid treatment in the 10 days before starting (and the study may exclude people who will need opioids during the study).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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