Kidney protection during heated chemotherapy surgery for ovarian cancer
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests two drugs (cilastatin and thiosulfate) to see which one better protects the kidneys during surgery that uses heated cisplatin chemotherapy directly in the abdomen. It is for women with advanced ovarian cancer whose disease is mostly in the belly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Female, aged 18 to 75 years
- Able to undergo major surgery (good overall health, normal or near-normal kidney and blood counts)
- Cancer is mostly in the abdomen (no spread to lungs or bones; limited spread to spleen or liver may be okay)
- Surgery team believes most or all visible tumors can be removed
- No allergy to platinum chemotherapy drugs
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether adding a special heated chemotherapy treatment during surgery (called HIPEC) improves outcomes for some people with ovarian, fallopian tube, or primary peritoneal cancer. It compares surgery alone versus surgery plus HIPEC after you’ve had chemotherapy first.
This trial tests a new way of combining chemotherapy and surgery to treat advanced ovarian, fallopian tube, or primary peritoneal cancer. It aims to see if giving chemotherapy directly into the abdomen during surgery (HIPEC) helps people live longer.
This trial looks at whether a heated chemotherapy treatment given in the abdomen during a planned second surgery (HIPEC) can improve outcomes for certain advanced ovarian cancers. It is for people who have already had initial chemotherapy and partially responded, with enough health to safely undergo surgery.
This trial tests giving heated chemotherapy directly into the belly during surgery for stomach cancer. It might help people with cancer that has spread to the lining of the belly but not to other organs.
This trial tests whether adding heated chemotherapy to the belly right after surgery can help people with stomach cancer live longer. It is done during the same operation, aiming to kill any remaining cancer cells.
This trial studies a planned surgery to remove as much cancer as possible, followed by heated chemotherapy placed in the belly (called HIPEC). It’s for people with recurrent mucinous ovarian cancer, aiming to control the cancer and improve outcomes.
Hear when a new Acute Kidney Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.