Kidney protection during heated chemotherapy surgery for ovarian cancer
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests two drugs (cilastatin and thiosulfate) to see which one better protects the kidneys during surgery that uses heated cisplatin chemotherapy directly in the abdomen. It is for women with advanced ovarian cancer whose disease is mostly in the belly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Female, aged 18 to 75 years
- Able to undergo major surgery (good overall health, normal or near-normal kidney and blood counts)
- Cancer is mostly in the abdomen (no spread to lungs or bones; limited spread to spleen or liver may be okay)
- Surgery team believes most or all visible tumors can be removed
- No allergy to platinum chemotherapy drugs
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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