7-Day treatment for H. pylori with new acid blocker and antibiotics
Part of Digestive system, Infections clinical trials.
This trial tests a 7-day combination of vonoprazan, high-dose amoxicillin, and bismuth to treat Helicobacter pylori infection in people who have never been treated for it before. The goal is to see if this short course is effective and safe for curing the infection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have tested positive for H. pylori in the last month using a breath test.
- You have chronic gastritis confirmed by an endoscopy in the last 3 months and need treatment based on current guidelines.
- You have never been treated for H. pylori before.
- You are willing to take the study medications and follow the study schedule.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a two-drug treatment (keverprazan and amoxicillin) for people who have H. pylori and have not been treated for it before. The goal is to see if this newer combination works well and is safe.
This trial compares two different antibiotic combinations to treat H. pylori, a common stomach bacteria that causes indigestion and ulcers. One uses a newer acid-blocking medicine (vonoprazan) and the other uses a standard one (esomeprazole), both paired with antibiotics.
This trial tests a new two-step antibiotic treatment for adults with chronic gastritis caused by H. pylori bacteria. If you have not been treated for H. pylori before and are between 18 and 70, you may be able to join.
This trial tests if a shorter 7-day treatment with two medicines (vonoprazan and amoxicillin) works as well as the standard 14-day course for H. pylori infection. It aims to find a simpler, shorter treatment option.
This trial tests a 14-day treatment using two medicines, vonoprazan and minocycline, to get rid of an H. pylori infection in the stomach. It aims to see if this combination is safe and works well, and might be a simpler option for people who haven't been treated for H. pylori before.
This study tests whether a new stomach acid medicine called vonoprazan, combined with different antibiotics, works better than standard treatments to clear an H. pylori infection. It is for people who have never been treated for H. pylori and want to try a shorter, simpler treatment course.
Hear when a new Helicobacter Pylori trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.