Pre-operative medication for tooth pain relief study
Part of Mouth & dental, Pain clinical trials.
This trial tests a medication called Trinase, given before a root canal, to see if it reduces pain after the procedure compared to a placebo. It may help if you have a painful tooth that needs treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a male between 18 and 50 years old.
- You are in good general health (no serious medical conditions).
- You have moderate to severe pain in a back tooth that needs a root canal.
- Your tooth has no signs of infection at the tip of the root on an x-ray.
- You are not allergic to Trinase or any of its ingredients (trypsin, bromelain, rutin).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares three different pain relievers to see which works best for pain after a single-visit root canal. It may help find better ways to manage post-procedure discomfort.
This study tests whether taking a pain reliever before a root canal reduces pain during and after the procedure. It may help people with severe tooth pain feel more comfortable during treatment.
This trial tests if using a saltwater solution (hypertonic saline) as a final rinse after a root canal can reduce pain afterward. It is for people needing a root canal on a lower premolar tooth that has a painful, inflamed nerve (symptomatic irreversible pulpitis).
This study compares different cleaning solutions used during root canal treatment to see which one reduces pain after treatment and has fewer bacteria. If you need root canal treatment, you may be able to join and help researchers understand the best way to care for infected teeth.
This study tests different medications placed inside a tooth's root canal during treatment to see which one best reduces pain afterward. If you have a tooth with a dead nerve (necrotic pulp), this trial might help determine the best way to manage your pain during the healing process.
This study tests whether a special cleaning solution (Triton Irrigation Protocol) reduces pain after root canal treatment in a dead lower molar. It may help people with a dead nerve tooth who want less discomfort after the procedure.
Hear when a new Postoperative Pain After Endodontic Treatment trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.