Pain relief choices after root canal treatment
Treatments studied
This study compares three different pain relievers to see which works best for pain after a single-visit root canal. It may help find better ways to manage post-procedure discomfort.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You are in good overall health.
- You have a specific type of tooth pain (called symptomatic irreversible pulpitis) in a lower premolar tooth.
- You have not taken any painkillers in the last 24 hours.
- You are not pregnant and have no other serious medical conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether taking a pain reliever before a root canal reduces pain during and after the procedure. It may help people with severe tooth pain feel more comfortable during treatment.
This trial tests a medication called Trinase, given before a root canal, to see if it reduces pain after the procedure compared to a placebo. It may help if you have a painful tooth that needs treatment.
This trial tests if using a saltwater solution (hypertonic saline) as a final rinse after a root canal can reduce pain afterward. It is for people needing a root canal on a lower premolar tooth that has a painful, inflamed nerve (symptomatic irreversible pulpitis).
This study tests two different pain medicines (trypsin-chymotrypsin and naproxen sodium) to see which one works better for pain after a root canal. It may help you if you need a root canal and are generally healthy.
This trial tests different methods for cleaning a tooth's root canal to see which one causes less pain after the procedure. It may help people with tooth pain caused by nerve inflammation.
This study compares two different instrument techniques used during root canal treatment to see which one leads to less pain afterward. It aims to help people with a type of tooth infection called irreversible pulpitis find a more comfortable recovery.
Hear when a new Symptomatic Irreversible Pulpitis (SIP) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.