Stopping immunosuppressants in older adults with ulcerative colitis in remission
Part of Digestive system clinical trials.
This study looks at whether it is safe to stop taking an immunosuppressant medication in older adults (60+) with ulcerative colitis that has been in remission for a long time. By stopping the drug, they hope to reduce side effects while keeping the disease under control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 60 years old or older.
- You must have had ulcerative colitis in remission (no active symptoms) for at least 1 year, and your doctor has confirmed this with a scope test.
- You must have been taking an immunosuppressant medication (azathioprine or mercaptopurine) for at least 5 years, with a stable dose for the past year.
- You need to have had a recent colonoscopy (within 6 months) showing no active inflammation.
- Your stool test (calprotectin) must show low inflammation levels.
- You must not have taken biologic drugs (like infliximab, vedolizumab) or JAK inhibitors in the past.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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