Stopping 5-ASA in stable inflammatory bowel disease
Part of Digestive system clinical trials.
This trial tests if patients with ulcerative colitis or Crohn's disease who are already stable on stronger medications (biologics or immunomodulators) can safely stop taking their 5-ASA (mesalamine) pill. It aims to see if stopping 5-ASA affects disease control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with ulcerative colitis or Crohn's disease.
- You have been on a biologic or an immunomodulator (like azathioprine or methotrexate) for at least 3 months.
- You have been on a stable dose of 5-ASA (mesalamine) for at least 3 months.
- Your inflammatory bowel disease has been in remission (no active symptoms) for at least 3 months.
- You are 19 years or older.
- You have not had any recent changes to your medications (like steroids or antibiotics) in the last 4 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if older adults with ulcerative colitis who have been in remission for a long time can safely stop taking their immune-suppressing medication (thiopurine). It may help reduce medication side effects while keeping the disease under control.
This trial tests whether people with ulcerative colitis who have been in deep remission (no signs of active disease) can safely reduce or stop their current medication. It aims to find out if careful monitoring can keep them healthy without full-dose treatment.
This study tests whether it is safe to stop taking acid-reducing pills (PPIs) for people with inactive IBD. If you have been on a PPI for over 6 months and your IBD is stable, you may be able to join.
This trial tests new therapies for people with moderate to severe Crohn's disease or ulcerative colitis. It may help if your standard treatments aren't working well enough.
This study tests an experimental tablet for people with moderate to severe ulcerative colitis that hasn't improved with standard treatments. It aims to see if the tablet can reduce symptoms and inflammation.
This trial tests whether a medicine applied to the pouch after surgery can prevent pouchitis (inflammation of the pouch) in people with ulcerative colitis who have had their colon removed and a pouch created. It may help avoid the discomfort and complications of pouchitis.
Hear when a new Crohn's Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.