Clin2
NCT07254416Possibly a fitNot yet recruiting

Preventing nausea and vomiting from T-DXd in breast cancer

Breast Cancer Patients Treated With T-DXd

Treatments studied

Part of Cancer, Digestive system clinical trials.

This study is looking at whether a specific medication can help prevent or reduce nausea and vomiting caused by the breast cancer drug T-DXd (trastuzumab deruxtecan). If you are starting T-DXd for the first time, this study might help you manage those side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
120 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years old or older
  • You must have a confirmed diagnosis of breast cancer
  • You must be about to receive your first full dose of the anti-cancer drug T-DXd (trastuzumab deruxtecan)
  • You must be able to take care of yourself and be up and about (a score of 2 or lower on the ECOG scale)
  • You must agree to follow the study rules and give written consent
  • You cannot be taking certain other medications that might affect nausea or vomiting (like other anti-nausea drugs, opioids, or psychiatric drugs)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07132749Enrolling by invitation
NEPA for nausea prevention during T-DXd in advanced HER2+ or HER2-low breast cancer

This trial tests whether the anti-nausea combination NEPA (netupitant and palonosetron) can prevent nausea and vomiting caused by the targeted therapy T-DXd in people with advanced HER2-positive or HER2-low breast cancer. It may help you if you are about to start T-DXd for the first time and want to manage treatment side effects.

Seoul, Gangnam-gu
NCT07828054Not yet recruiting· Phase 3
Steroid premedication to protect lungs during breast cancer treatment

This trial tests whether a steroid called dexamethasone, given before T-DXd, can reduce the risk of a rare but serious lung side effect (interstitial lung disease) in people with advanced breast cancer. If it works, it may make treatment safer.

NCT07035353Not yet recruiting
T-DXd for advanced HER2 breast cancer

This study is testing a drug called T-DXd (a targeted therapy) in people with advanced breast cancer that has HER2 overexpression or underexpression. It looks at how well the drug works in real-world settings, which may provide a new treatment option if your cancer has progressed.

NCT07782086Not yet recruiting
Study of T-DXd for advanced breast cancer with very low HER2

This study tests a drug called T-DXd (trastuzumab deruxtecan) for people with advanced breast cancer that has very low levels of HER2 (a protein that helps cancer grow) and that is also hormone receptor positive. The goal is to see if this drug can help shrink or slow the cancer.

Hefei, Anhui
NCT06210776Recruiting
Study of T-DXd in Chinese breast cancer patients

This study looks at how well Trastuzumab Deruxtecan (T-DXd) works in Chinese women with breast cancer that has spread. It is for people whose cancer is either HER2-positive or HER2-low and who have already had some treatment.

Beijing
NCT07195344Recruiting· Phase 4
T-DXd for breast cancer: comparing drug levels by BMI

This trial studies how the drug T-DXd (trastuzumab-deruxtecan) works in people with advanced or metastatic breast cancer. It compares drug levels in the body based on body mass index (BMI) to see if dose adjustments are needed.

Angers

Hear when a new Breast Cancer Patients Treated With T-DXd trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.