Dexmedetomidine effects during propofol anesthesia
This study tests whether adding a sedative called dexmedetomidine changes brain activity during general anesthesia. It aims to improve how anesthesia is given.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be scheduled for general anesthesia using propofol, remifentanil, and dexmedetomidine given by computer-controlled pumps.
- You cannot have a neurological disease (like epilepsy, Parkinson's, or stroke).
- You cannot have a psychiatric disease (like depression or anxiety that requires treatment).
- You must not be obese (body mass index over 30).
- You will not receive regional anesthesia (like an epidural or nerve block) during the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if dexmedetomidine, a sedative medication, can reduce pain and prevent confusion (delirium) after planned brain surgery. It may help you recover more comfortably.
This trial tests whether using one sleep medicine (propofol) alone works as well as using it with another medicine (dexmedetomidine) for children getting an MRI. The goal is to find the safest and most effective way to help kids stay still during the scan.
This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.
This trial tests whether a drug called dexmedetomidine, given during general anesthesia, helps keep your heart rate and blood pressure stable during outpatient surgery. It may be an option if you are having a minor surgery and are not on certain heart medications.
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
This study tests two sedation medicines (dexmedetomidine and propofol) used to keep patients calm and comfortable during cataract surgery. Researchers want to see which combination works best and is safest for this common procedure.
Hear when a new Adjuvants, Anesthesia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.