Clin2
NCT07261527Possibly a fitNot yet recruiting

Skin and fat changes from microneedling with or without a collagen booster

Skin Texture

Part of Skin clinical trials.

This study compares two ways to improve facial appearance: a treatment that uses tiny needles and heat (microneedling radiofrequency) alone, or with a substance called poly-L-lactic acid that helps your skin make more collagen. It looks at how the skin and facial fat change after treatment.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are interested in facial rejuvenation for cosmetic reasons.
  • You have not had fillers or energy-based facial treatments in the last 6 months.
  • You have not had any previous facial surgery.
  • You are not pregnant or breastfeeding.
  • You do not have active skin infections, dermatitis, open sores, eczema, or rosacea on your face.
  • You have no history of keloids or abnormal scarring, and are not allergic to poly-L-lactic acid.
  • You are not taking weight-loss medications like Ozempic or semaglutide.
  • You are not HIV positive and not taking HIV medications.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07471854Not yet recruiting
Comparing fat injections and skin needling for acne scars

This trial tests three ways to treat acne scars on the cheeks: using your own fat, fat with platelet-rich fibrin, or fat with microneedling. The goal is to see which combination works best and is safe.

NCT06640998Enrolling by invitation
Matrix pro for eyebrow and neck lift

This trial tests a radiofrequency microneedling device called Matrix Pro to lift droopy eyebrows and tighten loose skin under the chin and neck. It may help if you have mild to moderate skin laxity and are willing to avoid other cosmetic treatments during the study.

Marlborough, Massachusetts
NCT07225348Recruiting· Phase 4
Treating mouth wrinkles with microneedling and a topical gel

This study tests a treatment for wrinkles around the mouth using a special gel (poly-L-lactic acid) applied with a microneedling device. It may help reduce wrinkles without surgery.

Chestnut Hill, Massachusetts
NCT07221461Not yet recruiting· Phase 2
Skin filler for skin quality in women on GLP-1 medications

This study tests whether a hyaluronic acid filler (a common wrinkle-smoothing treatment) can improve skin quality in women who are taking GLP-1 medications for weight or diabetes. It aims to see if the filler can help with common skin changes like loss of firmness and wrinkles.

San Diego, California
NCT07151859Recruiting
Skin hydration trial for face, neck, or chest

This study tests a polynucleotide-based injection to improve skin hydration in one area of the face, neck, or chest. It may be an option if you have healthy skin and are looking for a non-surgical way to boost moisture.

Naples, Italy
NCT07478198Enrolling by invitation
PLLA injections for facial sagging after weight loss drug use

This trial tests whether PLLA injections can safely improve facial sagging in people who lost weight on GLP-1 drugs. If you are between 30 and 60, have noticeable sagging or smile lines, and have not had other facial treatments recently, this may be an option.

Shanghai, Shanghai Municipality

Hear when a new Skin Texture trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.