PLLA injections for facial sagging after weight loss drug use
Part of Skin clinical trials.
This trial tests whether PLLA injections can safely improve facial sagging in people who lost weight on GLP-1 drugs. If you are between 30 and 60, have noticeable sagging or smile lines, and have not had other facial treatments recently, this may be an option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 30 to 60 years old.
- You have been on a GLP-1 weight loss drug and lost significant weight (BMI down at least 5%).
- You have noticeable facial sagging or deep smile lines (rated moderate to severe).
- You have not had facial fillers, Botox, threads, or surgery in the treatment area within the past 1 to 2 years.
- You do not have active skin infections, allergies to the product or anesthetics, or a bleeding disorder.
- You are not pregnant, breastfeeding, or planning pregnancy during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests injections to tighten and lift loose, sagging skin that develops after bariatric (weight loss) surgery. The injections use a substance called PLLA to stimulate your body's natural skin-rebuilding process.
This study tests a treatment called Poly-L-lactic acid (PLLA) injections to help tighten loose skin on the neck. It is a small study looking at how well it works for Thai people aged 30 to 60.
This study tests a new way to reshape the jawline using poly-L-lactic acid, a substance that helps your skin produce more collagen. It might be an option if you are unhappy with lost definition in your jaw area due to aging.
This trial studies the safety of injectable biosimulators (PLLA and CAHA) used to treat loose skin or lost volume. It aims to see how these treatments interact with your body.
This trial tests whether a facial filler called Radiesse can restore volume lost during weight loss from GLP-1 medications (like Wegovy or Mounjaro). It's for adults just starting GLP-1 therapy who expect to lose 20 pounds or more and want to see if fillers can help their face look fuller.
This trial tests a new filler to treat moderate to severe smile lines (nasolabial folds). It aims to see if it works well for smoothing those lines.
Hear when a new Facial Skin Laxity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.