Entinostat plus chemotherapy for advanced bladder cancer
Treatments studied
Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether adding an experimental drug called entinostat to standard chemotherapy can help people with advanced bladder cancer whose first treatment has stopped working. It aims to see if this combination can shrink tumors or slow the cancer's growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your bladder cancer must be advanced or spread to other parts of the body and cannot be removed with surgery.
- You must have already tried one first-line treatment (like immunotherapy or chemotherapy) and it no longer worked.
- You need to have at least one tumor that can be measured on a scan.
- You must be willing to provide a tumor sample (either from a past biopsy or a new one).
- You should be in good enough health to carry out daily activities (ECOG 0 or 1) and have a life expectancy of at least 6 months.
- It's important that you have not had platinum-based chemotherapy (cisplatin or carboplatin) in the last 24 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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