Entinostat plus chemo for advanced bladder cancer
Treatments studied
Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests a new drug called entinostat combined with standard chemotherapy for bladder cancer that has spread and no longer responds to the first treatment. It may help shrink tumors or slow the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your bladder cancer must be the common type (not squamous or glandular).
- You’ve tried one first treatment for advanced cancer, and it didn’t work (but you haven’t had platinum chemotherapy afterward).
- You have at least one tumor that can be measured on a scan.
- You have stored tumor tissue from a past biopsy, or can get a new one.
- You are active enough to do daily tasks (ECOG score 0 or 1) and expected to live at least 6 more months.
- If you could become pregnant, you agree to use birth control during the study and for 6 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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