Clin2
NCT07261683Possibly a fitRecruiting

Combination therapy for recurrent ovarian cancer

Ovarian CancerImmunotherapyPembrolizumab

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This trial tests a new combination of chemotherapy, immunotherapy, and a bladder relaxant for ovarian cancer that has come back after initial treatment. It aims to see if adding these drugs together can help control the cancer longer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
20 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have ovarian, fallopian tube, or primary peritoneal cancer that has come back after initial treatment.
  • Your last treatment included a platinum-based chemotherapy, and it has been less than 12 months since that treatment ended.
  • You are able to do daily activities without help (ECOG score 0 or 1).
  • You have not had prior treatment with certain immunotherapies (like PD-1 or PD-L1 inhibitors).
  • You are willing to provide a tumor tissue sample from a past surgery or a new biopsy.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07714668Recruiting· Phase 2
Combination therapy for recurrent ovarian cancer

This study tests a new combination treatment for ovarian cancer that has come back after earlier treatment. It aims to see if the combination can shrink tumors or slow the disease, and it may be an option for people whose cancer has become resistant to platinum-based chemotherapy.

Shanghai, Shanghai Municipality
NCT07634094Not yet recruiting· Phase 2
Chemotherapy, vaccine, and immunotherapy for advanced ovarian cancer

This trial tests a combination treatment for advanced ovarian cancer that hasn't been treated before. It combines chemotherapy, a personalized vaccine made from your own immune cells, and a drug called pembrolizumab to help your immune system fight the cancer.

Pittsburgh, Pennsylvania
NCT07776171Not yet recruiting· Phase 2
Studying a new drug combo for recurrent ovarian cancer after prior treatments

This trial tests a new combination of drugs (trastuzumab rezetecan and carboplatin, with or without bevacizumab) against standard chemotherapy for women with recurrent ovarian, fallopian tube, or primary peritoneal cancer. It’s for those who have already had platinum-based chemo and a PARP inhibitor, and whose cancer came back after a treatment-free interval of at least 6 months.

Guangzhou, Guangdong
NCT06840002Recruiting· Phase 1/Phase 2
Targeted drug plus chemotherapy for recurrent ovarian cancer

This trial tests a new targeted drug, SHR-A1811, combined with chemotherapy for women whose ovarian cancer has returned but still responds to platinum-based drugs. The goal is to see if the combination works better than chemotherapy alone.

Wuhan, Hubei
NCT06600841Not yet recruiting· Phase 2
Study of adebrelimab, fuzuloparib, and chemo for resistant ovarian cancer

This trial tests a new combination of drugs for ovarian cancer that has come back quickly after platinum-based chemo. The goal is to see if adding an immunotherapy and a targeted pill to non-platinum chemo can help shrink tumors.

Fuzhou, Fujian
NCT07720180Not yet recruiting· Phase 2
Immune cell therapy for recurrent ovarian cancer

This trial tests a new approach using your own immune cells (tumor-infiltrating lymphocytes) that have been modified to work better, followed by a combination of oral chemo and immunotherapy. It's for people with ovarian cancer that has come back after standard treatment.

Charleston, South Carolina

Hear when a new Ovarian cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.