Clin2
NCT07265739Possibly a fitNot yet recruiting

Losartan and paclitaxel for platinum-resistant ovarian cancer

Platinum Resistant Ovarian Cancer

Treatments studied

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This trial tests whether adding losartan, a blood pressure medication, to the chemotherapy drug paclitaxel can help treat ovarian cancer that has returned after platinum-based treatment. The goal is to see if this combination can slow or stop the cancer's growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
27 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have advanced ovarian, fallopian tube, or primary peritoneal cancer that has returned within 6 months of completing platinum-based chemotherapy.
  • You have at least one tumor that can be measured on a scan or exam.
  • You have received no more than 4 prior lines of treatment for platinum-resistant disease.
  • You are generally well enough to carry out daily activities (ECOG performance status 0-2).
  • Your blood counts, kidney, and liver function are within required limits.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06815497Recruiting· Phase 2
Telmisartan plus chemo for platinum-resistant ovarian cancer

This trial tests adding telmisartan (a blood pressure medicine) to standard chemotherapy for people with ovarian cancer that no longer responds to platinum-based drugs. The goal is to see if the combination can help control the cancer better.

Lebanon, New Hampshire
NCT06964009Recruiting· Phase 1
New drug plus paclitaxel for resistant ovarian cancer

This trial tests a new drug called DT2216 combined with the chemotherapy drug paclitaxel for ovarian cancer that has stopped responding to platinum-based chemo. The goal is to see if this combination can shrink or slow the cancer, and to find a safe dose.

Boston, Massachusetts
NCT06867562Not yet recruiting· Phase 3
Paclitaxel liquid for platinum-resistant ovarian cancer

This study tests a new liquid form of paclitaxel (a common chemotherapy drug) in women whose ovarian, fallopian tube, or primary peritoneal cancer has stopped responding to platinum-based chemotherapy. The goal is to see if this new formulation is safe and effective for this difficult-to-treat situation.

NCT04055649Recruiting· Phase 2
Test of ONC201 and weekly paclitaxel for platinum-resistant ovarian cancer

This Phase 2 study tests whether ONC201 given with weekly paclitaxel can control platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer. It may help by shrinking tumors or slowing growth in people whose cancer has progressed after platinum chemotherapy.

Detroit, Michigan
NCT06840002Recruiting· Phase 1/Phase 2
Targeted drug plus chemotherapy for recurrent ovarian cancer

This trial tests a new targeted drug, SHR-A1811, combined with chemotherapy for women whose ovarian cancer has returned but still responds to platinum-based drugs. The goal is to see if the combination works better than chemotherapy alone.

Wuhan, Hubei
NCT07286266Recruiting· Phase 3
Testing a new drug for platinum-resistant ovarian cancer

This phase 3 trial tests a new drug, mocertatug rezetecan, against standard treatments for ovarian cancer that no longer responds to platinum chemo. It's for people who have had 1 to 4 prior therapies and may offer a new option if you haven't tried all standard treatments yet.

Randwick, New South Wales

Hear when a new Platinum-resistant Ovarian Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.