Liver function and study drug processing
Part of Digestive system, Hormones & metabolism clinical trials.
This study looks at how the medicine PF-07328948 is processed by people with different levels of liver function. It includes both healthy people and those with stable liver disease (classified as mild, moderate, or severe). The goal is to see if the liver condition affects how the drug works in the body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You must not be able to become pregnant (if female) or father a child (if male).
- Your body mass index (BMI) must be between 17.5 and 40, and you must weigh at least 99 pounds.
- If you have liver disease, it must be stable and fit one of three severity levels (mild, moderate, or severe).
- If you have liver disease, you cannot have certain complications like liver cancer, severe fluid buildup, or a recent bleeding episode.
- You must not have HIV, hepatitis B or C (unless you are in the healthy group), or poor kidney function.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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