Study of PF-08653944 in People With and Without Liver Problems
Treatments studied
This is an early-stage study testing a new medicine called PF-08653944 in healthy adults and in people with varying degrees of liver function problems. The goal is to understand how the medicine works in the body and how liver function affects how the body processes it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 75 years old
- Have a BMI (body mass index) of 21 or higher and weigh more than 50 kg (about 110 pounds)
- Not be pregnant, breastfeeding, or planning to become pregnant during the study; women must use effective birth control
- Have no serious medical or psychiatric conditions, including recent thoughts of suicide
- Not have taken GLP-1 receptor agonist medicines (like Ozempic or Mounjaro) in the past 90 days
- Not be currently enrolled in another drug study or have received an experimental drug in the past 30 days
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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