Medication for irritability in children with autism
Part of Mental health clinical trials.
This study tests a new medication to help reduce irritability in children and teenagers with autism spectrum disorder. The medication may improve mood and behavior, making daily life easier for the child and family.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of autism spectrum disorder (ASD) and have symptoms of irritability.
- Your irritability score is high enough (18 or more on a standard scale) and your doctor also rates your irritability as significant.
- You do not have a current diagnosis of bipolar disorder, schizophrenia, schizoaffective disorder, major depression, or post-traumatic stress disorder.
- If you have ADHD, it must not be the main condition, and it should be well-managed and stable.
- You must not have any other serious medical conditions or abnormal lab results that could make the study unsafe for you.
- You must not be at risk for suicidal behavior.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new medicine, KarXT, to see if it can help reduce irritability in children and teenagers with autism. It aims to improve symptoms like anger, aggression, and mood swings.
This study tests an investigational medication called lumateperone to see if it can reduce irritability in children and teens with autism. It is for teenagers aged 13–17 whose irritability is causing significant problems.
This study tests a new medication called Lumateperone to see if it can reduce irritability in children and teens with autism. It's a 3-month trial that compares the study drug to a placebo (a pill with no active medicine) to find out if it helps with mood and behavior.
This study tests a new drug combination (KarXT + KarX-EC) to see if it can safely reduce agitation in people with Alzheimer's disease. It may help if you or your loved one has bothersome agitation that affects daily life.
This study tests a combination medicine (xanomeline and trospium chloride) to see if it is safe and tolerable over a longer period for children and adolescents with psychiatric disorders, especially those with autism-related irritability. It may help families understand if this treatment can be used beyond the initial study period.
This trial tests if a new medicine, KarXT, can safely and effectively treat schizophrenia in adolescents. It may help teenagers who have active symptoms like hallucinations or disorganized thinking.
Hear when a new Irritability Associated With Autism Spectrum Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.