Precision Medicine in Achalasia (PREMEDIA) Study
Part of Digestive system clinical trials.
This study at Northwestern University is looking for people with certain severe esophageal motility disorders (like achalasia) to see if a personalized medicine approach can improve treatment. It focuses on those who haven't had prior surgery or recent endoscopic treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must have a specific type of esophageal motility disorder: type III achalasia, spastic EGJOO, Jackhammer esophagus, or distal esophageal spasm.
- Your Eckardt score (measuring swallowing difficulty, chest pain, and weight loss) must be greater than 3.
- You cannot have had prior POEM or other surgical treatment for achalasia.
- No endoscopic dilation or Botox injection for achalasia in the last 6 months.
- No prior stomach or esophageal surgeries, including weight-loss or GERD procedures, or other conditions like cancer-related swallowing problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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