Clin2
NCT07309185Possibly a fitRecruiting

Adebrelimab, famitinib, and irinotecan for advanced stomach cancer

Stomach Neoplasms

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a combination of three drugs (adebrelimab, famitinib, and irinotecan) for people with advanced stomach or gastroesophageal junction cancer that got worse after first-line treatment. It may offer a new option if you have already tried standard therapy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
66 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have advanced stomach or gastroesophageal junction cancer confirmed by biopsy.
  • You have already tried and failed first-line treatment that included chemotherapy and an immunotherapy drug, and you used the immunotherapy for at least 3 months.
  • You have at least one tumor that can be measured on scans and has not been treated with radiation (or has grown after radiation).
  • Your overall health is good enough for daily activities (ECOG score 0 or 1) and your doctor expects you to live at least 12 more weeks.
  • Your blood counts, liver, and kidney function are within specific ranges (your doctor will check these with lab tests).
  • You are not pregnant and agree to use effective birth control during and for 6 months after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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