Clin2
NCT07313202Possibly a fitNot yet recruiting

Ivarmacitinib for advanced solid tumors after immunotherapy side effects

Patients With Advanced Solid Tumors Who Discontinued Treatment Due to irAE

Treatments studied

Part of Cancer, Immune system & allergy clinical trials.

This study tests a pill called Ivarmacitinib (a JAK inhibitor) for people with advanced solid tumors who had to stop immunotherapy because of side effects. The drug aims to calm the immune system and may help you restart cancer treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
72 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have stopped an immunotherapy drug (like a PD-1 or PD-L1 inhibitor) because of side effects.
  • Your side effects from immunotherapy can be either still active (and you are on steroids) or mostly resolved (within 3 months of stopping).
  • You need to have adequate organ function, such as normal blood counts, kidney, and liver tests.
  • You must be willing to use reliable birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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