Testing ondansetron for comfort during emergency stomach bleeding exam
Part of Digestive system clinical trials.
This trial tests whether a nausea medicine called ondansetron helps people feel better and lets doctors work more efficiently during a camera test (endoscopy) for upper GI bleeding. If you need an emergency endoscopy for bleeding, ondansetron may reduce discomfort.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have likely bleeding from the upper part of your digestive tract (stomach or esophagus)
- Your doctor has scheduled an emergency upper endoscopy (a camera test) to find and treat the bleeding
- You are not severely ill with another major health problem (like severe heart, lung, kidney, or brain disease)
- You are not pregnant
- You have not been diagnosed with severe depression, severe anxiety, or a past heart rhythm problem
- You are not allergic to the medicines dyclonine (a numbing throat spray) or ondansetron (a nausea medicine)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a combination of a nausea medicine (ondansetron) and a numbing spray (dyclonine) can make having a stomach scope test more comfortable for people who are awake during it.
This Phase 3 trial tests whether ondansetron (a medicine used to reduce nausea and vomiting) works better than a placebo, along with usual care, for adults with acute gastroenteritis. It also checks how safe ondansetron is in this setting, especially for the heart rhythm and other side effects.
This trial tests whether using a bedside ultrasound to guide IV fluids, along with a nausea medicine called ondansetron, can prevent blood pressure from dropping after starting general anesthesia. It may help people stay more stable during elective surgeries.
This trial tests whether ondansetron can improve stomach “sensorimotor” problems—how the gut senses food and moves it—especially in people with diabetes and troubling indigestion. It may help reduce symptoms like early fullness, nausea, and discomfort after eating.
This trial tests whether ondansetron, a medicine that helps control nausea and vomiting, can reduce the risk of pancreatitis (inflammation of the pancreas) after an ERCP procedure. If you are scheduled for an ERCP and do not have certain health issues, you may be able to join.
This study tests two different medication combinations to prevent nausea and vomiting after laparoscopic gallbladder removal surgery. You'll receive either ondansetron plus metoclopramide, or dexamethasone plus metoclopramide, and researchers will track how quickly you need rescue medication if nausea occurs.
Hear when a new Upper Gastrointestinal Bleeding (UGIB) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.