Stem cell injections in the intestine for type 2 diabetes
Part of Hormones & metabolism clinical trials.
This trial tests a new treatment for type 2 diabetes where stem cells are injected into the duodenum (the first part of the small intestine) using an endoscope (a thin tube). The goal is to see if this procedure is safe and possible, and it might help improve your blood sugar control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You need to be between 25 and 70 years old if you have type 2 diabetes (or 18 to 75 if you are a healthy volunteer).
- If you have diabetes, you must have been diagnosed for at least one year and your average blood sugar (HbA1c) should be between 7.5% and 10%.
- Your body mass index (BMI) must be between 25 and 35 if you have diabetes, or below 25 if you are a healthy volunteer.
- You must have insulin resistance (a measure called HOMA-IR greater than 5) and a certain level of natural insulin production (fasting C-peptide at least 1).
- You need to be on a stable diabetes medication plan for the last 3 months.
- You cannot have certain health conditions like type 1 diabetes, celiac disease, a history of pancreatitis or stomach surgery, active infections, cancer, autoimmune diseases, or severe organ problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a device placed in the intestine to help control blood sugar and support weight loss in people with type 2 diabetes and obesity. It may offer a new option for managing both conditions together.
This study tests a new procedure that uses magnets to connect two sections of your small intestine. It aims to see if this approach can help improve blood sugar control and aid in weight management for people with type 2 diabetes who currently take oral medications.
This trial tests if a type of stem cell product (exosomes) can safely and effectively help people with type 2 diabetes. Researchers will give infusions to see if it improves blood sugar control and pancreatic function.
This study tests an experimental stem cell treatment (DT2-SCT) to see if it can improve blood sugar control in people with type 2 diabetes who need insulin. It is a double-blind study, so neither you nor the study team will know if you get the real treatment or a placebo.
This trial tests a new stem cell treatment for people with type 2 diabetes that is difficult to control with standard medications. The treatment uses a special kind of stem cell to try to improve blood sugar levels.
This trial tests using your own fat stem cells to help control blood sugar in type 2 diabetes. It might help if you have had diabetes for less than 10 years and are not on insulin.
Hear when a new Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.