Clin2
NCT07346677Possibly a fitNot yet recruiting

Sesame oil, nitroglycerin ointment, or aloe vera gel for vein irritation

CancerChemotherapy

Treatments studied

Part of Cancer, Heart & circulation clinical trials.

This study tests whether applying sesame oil, nitroglycerin ointment, or aloe vera gel to the skin can prevent vein irritation (phlebitis) caused by certain chemotherapy drugs given through a small tube in the arm. It may help reduce pain and swelling at the injection site.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
190 people
Ages
Any age
Study type
Interventional

Who can take part

  • You are an adult (18 or older) of any gender.
  • You are receiving chemotherapy with 5-fluorouracil or cisplatin through a small tube in your arm (peripheral IV).
  • You have breast cancer or colon cancer.
  • You do not already have vein irritation (phlebitis) at the injection site.
  • You are not using a port or a central line for your chemotherapy.
  • You are not receiving radiation therapy, immunotherapy, or palliative therapy, and you are not on certain other chemotherapy drugs (like antitumor antibiotics or plant alkaloids).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07387497Not yet recruiting
Palm stimulation for comfort during IV insertion

This study tests whether using a small palm-stimulating device during IV placement can reduce pain and fear in people receiving chemotherapy. If it works, it could make getting an IV more comfortable for you.

Malatya, Malatya
NCT05411666Recruiting
Optimizing care for a fully implanted chemotherapy vein port

This study focuses on the best way to maintain a fully implanted vein catheter (a port used for chemotherapy). It may help reduce complications and improve how safely your catheter is maintained after chemotherapy ends.

Braga
NCT04207437Recruiting
Daily handheld vibration therapy for chemotherapy nerve pain

This trial studies whether daily handheld vibration can lessen nerve damage symptoms in the hands after certain chemotherapy medicines. It may help reduce numbness, tingling, or pain from chemotherapy-related nerve problems.

Avon, Indiana
NCT07492654Not yet recruiting· Phase 4
Triethanolamine cream for preventing radiation vaginitis

This study tests whether a cream called triethanolamine can help prevent or treat vaginal irritation caused by radiation therapy for cervical cancer. If you are receiving radiation for cervical cancer, this treatment might reduce discomfort and improve your quality of life.

NCT07072468Recruiting· Phase 2
Test of a gel for nerve pain after chemotherapy

This study tests a new gel (VMD-3866) applied to the skin to treat moderate nerve pain, numbness, or tingling caused by previous chemotherapy. It aims to see if the gel can safely reduce pain for people whose symptoms have been stable for at least 8 weeks.

London, UK
NCT05642611Recruiting· Phase 3
Cooling and compression for nerve protection during chemotherapy

This study tests whether using cooling and/or compression on the arms or legs can prevent nerve damage that can happen from certain chemotherapy drugs. If you get eligible chemo soon, this may help lower the chance of painful numbness or tingling during treatment.

Birmingham, Alabama

Hear when a new Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.