Clin2
NCT07350928Possibly a fitRecruiting

Nasal spray before breast-saving surgery for calm wakefulness

Breast Cancer

Part of Cancer, Skin clinical trials.

This trial tests a nasal spray (dexmedetomidine) given before breast-conserving surgery to help you stay calm and comfortable while awake during the procedure. It aims to improve your recovery and waking experience after surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
394 people
Ages
20 years to 70 years
Study type
Interventional

Who can take part

  • You are a woman between 20 and 70 years old
  • You have breast cancer and are scheduled for breast-conserving surgery
  • You are in good general health (ASA I-II) with a BMI between 18 and 26
  • You do not have severe nasal problems, heart rhythm issues, asthma, or a history of stroke
  • You have not taken anti-anxiety medicines or sedatives recently
  • You are not pregnant, and have no history of drug or alcohol abuse

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05439005Recruiting· Phase 3
Opioid-free anesthesia for breast reconstructive flap surgery

This trial compares opioid-free anesthesia with opioid-based anesthesia during breast free-flap reconstruction surgery. It aims to see whether avoiding opioids can improve safety and comfort around the time of surgery.

Paris
NCT06671327Not yet recruiting· Phase 4
Dexmedetomidine for pain before, during, and after surgery

This trial tests whether giving a medicine called dexmedetomidine before surgery can reduce pain during and after the operation. It is for adults having non-cardiac surgery under general anesthesia.

Beijing, Beijing Municipality
NCT06566482Recruiting· Phase 4
Medicine for pain after surgery in sleep apnea patients

This trial tests a combination of two medicines (dexmedetomidine and esketamine) given in small doses to help with pain after surgery. It is for people who have sleep apnea or are at risk for it, and who are having chest or belly surgery with a scope.

Beijing, Beijing Municipality
NCT07298525Not yet recruiting· Phase 4
Safety of a sedative nasal spray before surgery with less monitoring

This trial tests a nasal spray sedative (dexmedetomidine) given before surgery to see if it's safe when there's less monitoring. It may help people who need general, spinal, or nerve block anesthesia feel calm and comfortable.

NCT06896721Not yet recruiting· Phase 4
Nasal dexmedetomidine for sedation and recovery in children having minor surgery

This trial tests a nasal spray medicine called dexmedetomidine to help children relax before surgery and reduce agitation after waking up. It also monitors brain activity during anesthesia to ensure safety and effectiveness.

NCT07324057Recruiting
Medication before surgery to reduce autism-related anxiety in children

This trial tests whether a nose spray given before anesthesia can help children with autism feel calmer and have fewer behavior problems after surgery. It compares two medications, dexmedetomidine and esketamine, to see if they reduce negative post-surgery changes.

Nanjing, Jiangsu

Hear when a new Breast cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.